摘要: Objectives To provide an overview of colorectal carcinoma (CRC), including current treatment strategies for various stages the disease. Data Sources Research articles and textbooks. Conclusions Despite screening methods early detection CRC, many patients present with late-stage disease have a poor prognosis. The approval irinotecan CRC changed approach to treatment, there are numerous agents under clinical evaluation that may soon be available management CRC. Implications Nursing Practice Recent advances in molecular targeting led development new treatments Because nurses will ultimately administer these agents, it is important understand how target
elsevier.com
sci-hub.se 参考文章(57)
R.A. Sharma, M.M. Manson, A. Gescher, W.P. Steward, Colorectal cancer chemoprevention: biochemical targets and clinical development of promising agents. European Journal of Cancer. ,vol. 37, pp. 12- 22 ,(2001) , 10.1016/S0959-8049(00)00326-9
Alfred M. Cohen, Sidney J. Winawer, Cancer of the colon, rectum, and anus McGraw-Hill. ,(1995)
Morton A. Meyers, Neoplasms of the digestive tract : imaging, staging, and management Lippincott-Raven. ,(1998)
Steven A. Rosenberg, Vincent T. DeVita, Samuel Hellman, Cancer : Principles and Practice of Oncology ,(1982)
Guido Francini, Roberto Petrioli, Luciano Lorenzini, Sergio Mancini, Salvatore Armenio, Gabriello Tanzini, Stefania Marsili, Antonietta Aquino, Giuseppe Marzocca, Serenella Civitelli, Lorenzo Mariani, Domenico De Sando, Sergio Bovenga, Marco Lorenzi, Folinic acid and 5-fluorouracil as adjuvant chemotherapy in colon cancer Gastroenterology. ,vol. 106, pp. 899- 906 ,(1994) , 10.1016/0016-5085(94)90748-X
Hugh J Freeman, Colorectal cancer complicating Crohn's disease. Canadian Journal of Gastroenterology & Hepatology. ,vol. 15, pp. 231- 236 ,(2001) , 10.1155/2001/934734
Paulo M. Hoff, Rafat Ansari, Gerald Batist, John Cox, Walter Kocha, Mario Kuperminc, Jean Maroun, David Walde, Charles Weaver, Evelyn Harrison, Hans U. Burger, Bruno Osterwalder, Alfred O. Wong, Ralf Wong, Comparison of Oral Capecitabine Versus Intravenous Fluorouracil Plus Leucovorin as First-Line Treatment in 605 Patients With Metastatic Colorectal Cancer: Results of a Randomized Phase III Study Journal of Clinical Oncology. ,vol. 19, pp. 2282- 2292 ,(2001) , 10.1200/JCO.2001.19.8.2282
François Meyer, Emily White, Alcohol and Nutrients in Relation to Colon Cancer in Middle-aged Adults American Journal of Epidemiology. ,vol. 138, pp. 225- 236 ,(1993) , 10.1093/OXFORDJOURNALS.AJE.A116851
Udo Vanhoefer, Andreas Harstrick, Wolf Achterrath, Shousong Cao, Siegfried Seeber, Youcef M. Rustum, Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview Journal of Clinical Oncology. ,vol. 19, pp. 1501- 1518 ,(2001) , 10.1200/JCO.2001.19.5.1501
James E. Krook, Charles G. Moertel, Leonard L. Gunderson, Harry S. Wieand, Roger T. Collins, Robert W. Beart, Theodore P. Kubista, Michael A. Poon, William C. Meyers, James A. Mailliard, Donald I. Twito, Roscoe F. Morton, Michael H. Veeder, Thomas E. Witzig, Stephen Cha, Subhash C. Vidyarthi, Effective Surgical Adjuvant Therapy for High-Risk Rectal Carcinoma New England Journal of Medicine. ,vol. 324, pp. 709- 715 ,(1991) , 10.1056/NEJM199103143241101