作者: Steven L. Sabin , Richard M. Rosenfeld , Krishnamurthi Sundaram , Gady Har-El , Frank E. Lucente
DOI: 10.1177/014556139907800813
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摘要: Previous studies have evaluated the effects of comorbidity on survival in patients with cancer. We applied Charlson index (CCI) to a cohort laryngeal cancer validate its use and assess prognostic impact age. Our study population consisted 152 who were seen over 10-year period. Patients assigned CCI scores categorized into low- high-grade groups for comparison. Age adjustments performed by adding 1 point score each decade median Low- vs. was valid predictor independent TNM (tumor, nodes, metastases) stage. Low-grade present 126 patients; their 41 months. High-grade 26 8 months (p = 0.0002). The addition age factor did not improve our ability. There no difference respect tobacco alcohol use, gender, treatment modality, or mean time recurrence. incidence severity complications also similar two groups. conclude that is strong confounding should be considered staging Further investigations are necessary validity this other head neck cancers.