作者: Hui Yao Lan
DOI:
关键词:
摘要: The present invention resides in the discovery that Smad3, a key downstream mediator of TGF-β signaling, plays critical role development and progression cancer. Thus, this application provides for novel method treating cancer by inhibiting Smad3 such as through administration SIS3, an inhibitor Smad3. Further provided are compositions kits useful way signaling.