Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer

作者: Jerson L. Silva , Elio A. Cino , Iaci N. Soares , Vitor F. Ferreira , Guilherme A. P. de Oliveira

DOI: 10.1021/ACS.ACCOUNTS.7B00473

关键词:

摘要: … , generating aggregates. The mutant form of tumor suppressor protein, p53, has recently been shown to exhibit prion-like properties. Within the context of p53 aggregation and the …

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