Defense Mechanisms of Tears and Ocular Surface

作者: A.M. McDermott

DOI: 10.1016/B978-0-12-374203-2.00057-9

关键词:

摘要: Despite constant exposure to the environment ocular surface rarely becomes infected. This immunity is conferred by a variety of physical and chemical mechanisms that cooperate limit pathogen entry kill or prevent proliferation microbes. article provides an overview major operating in tears bathe surface. These are primarily include antimicrobials such as lysozyme secretory immunoglobulin A. The contributions from corneal conjunctival epithelial cells also addressed encompass barrier created themselves production antimicrobial peptide defensins LL-37.

参考文章(11)
Alison M. McDermott, The Role of Antimicrobial Peptides at the Ocular Surface Ophthalmic Research. ,vol. 41, pp. 60- 75 ,(2009) , 10.1159/000187622
Pedram Hamrah, M. Reza Dana, Corneal Antigen-Presenting Cells Chemical immunology and allergy. ,vol. 92, pp. 58- 70 ,(2007) , 10.1159/000099254
Linda D. Hazlett, Bacterial Infections of the Cornea (Pseudomonas aeruginosa) Chemical immunology and allergy. ,vol. 92, pp. 185- 194 ,(2007) , 10.1159/000099269
Robert A. Sack, Irene Nunes, Ann Beaton, Carol Morris, Host-defense mechanism of the ocular surfaces. Bioscience Reports. ,vol. 21, pp. 463- 480 ,(2001) , 10.1023/A:1017943826684
Garima Gupta, Avadhesha Surolia, Collectins: sentinels of innate immunity BioEssays. ,vol. 29, pp. 452- 464 ,(2007) , 10.1002/BIES.20573
David J. Evans, Nancy A. McNamara, Suzanne M.J. Fleiszig, Life at the front: dissecting bacterial-host interactions at the ocular surface. Ocular Surface. ,vol. 5, pp. 213- 227 ,(2007) , 10.1016/S1542-0124(12)70612-2
J FLANAGAN, M WILLCOX, Role of lactoferrin in the tear film. Biochimie. ,vol. 91, pp. 35- 43 ,(2009) , 10.1016/J.BIOCHI.2008.07.007
On a Remarkable Bacteriolytic Element Found in Tissues and Secretions Proceedings of The Royal Society B: Biological Sciences. ,vol. 93, pp. 306- 317 ,(1922) , 10.1098/RSPB.1922.0023
Fu-Shin X. Yu, Linda D. Hazlett, Toll-like receptors and the eye. Investigative Ophthalmology & Visual Science. ,vol. 47, pp. 1255- 1263 ,(2006) , 10.1167/IOVS.05-0956
Friedrich P. Paulsen, Monica S. Berry, Mucins and TFF peptides of the tear film and lacrimal apparatus. Progress in Histochemistry and Cytochemistry. ,vol. 41, pp. 1- 53 ,(2006) , 10.1016/J.PROGHI.2006.03.001