A Brief Screening Tool to Assess the Risk of Contracting HIV Infection Among Active Injection Drug Users

摘要: Objective To incorporate preexposure prophylaxis and other biomedical or intensive behavioral interventions into the care of injection drug users (IDUs), health providers need validated, rapid, risk screening tools for identifying persons at highest incident HIV infection. Methods develop validate a brief tool assessing contracting (ARCH), we included test data from 1904 initially HIV-uninfected men women enrolled followed in AIDS Linked to Intravenous Experience prospective cohort study between 1988 2008. Using logistic regression analyses with generalized estimating equations, identified significant predictors infection, then rescaled summed their coefficients create score. Results The final model age, engagement methadone maintenance program, composite score obtained by counting number following 5 behaviors reported during past 6 months: heroin, cocaine, sharing cooker, needles, visiting shooting gallery. area under receiver operating characteristic curve was 0.720; possible scores on index ranged 0 100 46 greater had sensitivity 86.2% specificity 42.5%, appropriate tool. Discussion We developed an easy administer 7-question cutoff that is predictive infection large IDUs Baltimore. ARCH-IDUs can be used prioritize who are injecting illicit drugs consideration prevention efforts.