The levels of liver enzymes and atypical lymphocytes are higher in youth patients with infectious mononucleosis than in preschool children.

作者: Yan Wang , Jun Li , Yuan-yuan Ren , Hong Zhao

DOI: 10.3350/CMH.2013.19.4.382

关键词:

摘要: Background/Aims: Infectious mononucleosis (IM) is the clinical presentation of primary infection with Epstein-Barr virus. Although literature contains a massive amount information on IM, most this related specifically to only children or adults separately. In order distinguish any differences between preschool and youth patients, we retrospectively analyzed their demographic features. Methods: Records patients hospitalized from December 2001 September 2011 diagnosis IM were retrieved Peking University First Hospital, which tertiary teaching hospital in Beijing. The data characteristics collected. Results: was diagnosed 287 during 10-year period, incidence peaks among (≤7 years old, 130/287, 45.3%) (>15 <24 101/287, 35.2%). complaints at admission did not differ these two patient groups, signs (tonsillopharyngitis, lymphadenopathy, hepatomegaly, edema eyelids) much higher children. liver lesion percentage atypical lymphocytes significantly group (P<0.001), average stay longer group. Pneumonia common complication, there no case mortality. Conclusions: Beijing, China. levels enzymes increase age.

参考文章(22)
C Cheng, L Chang, P Shao, P Lee, J Chen, C Lu, C Lee, L Huang, Clinical manifestations and quantitative analysis of virus load in Taiwanese children with Epstein-Barr virus-associated infectious mononucleosis. Journal of Microbiology Immunology and Infection. ,vol. 40, pp. 216- 221 ,(2007)
H. O. Kangro, H. K. Osman, Y. L. Lau, R. B. Heath, C. Y. Yeung, M. H. Ng, Seroprevalence of antibodies to human herpesviruses in England and Hong Kong Journal of Medical Virology. ,vol. 43, pp. 91- 96 ,(1994) , 10.1002/JMV.1890430117
Napoleón González Saldaña, Victor Monroy Colín, Georgina Piña Ruiz, Hugo Juárez Olguín, Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Research Notes. ,vol. 5, pp. 361- 361 ,(2012) , 10.1186/1756-0500-5-361
Uta Drebber, Hans U. Kasper, Joanna Krupacz, Katharina Haferkamp, Michael A. Kern, Hans M. Steffen, Maria Quasdorff, Axel zur Hausen, Margarete Odenthal, Hans P. Dienes, The role of Epstein–Barr virus in acute and chronic hepatitis Journal of Hepatology. ,vol. 44, pp. 879- 885 ,(2006) , 10.1016/J.JHEP.2006.02.006
Kengo Takeuchi, Keiko Tanaka-Taya, Yukumasa Kazuyama, Yoichi M. Ito, Shuji Hashimoto, Masashi Fukayama, Shigeo Mori, Prevalence of Epstein-Barr virus in Japan: trends and future prediction. Pathology International. ,vol. 56, pp. 112- 116 ,(2006) , 10.1111/J.1440-1827.2006.01936.X
CHUN WING CHAN, ALAN KWOK SHING CHIANG, KWOK HUNG CHAN, ALLAN SIK YIN LAU, Epstein-Barr virus-associated infectious mononucleosis in Chinese children. Pediatric Infectious Disease Journal. ,vol. 22, pp. 974- 978 ,(2003) , 10.1097/01.INF.0000095199.56025.96
Shinya Hara, Yo Hoshino, Takehito Naitou, Kenichi Nagano, Masakatsu Iwai, Kazuyuki Suzuki, Kazuhide Yamamoto, Tetsuro Nagasaka, Tsuneo Morishima, Hiroshi Kimura, Association of virus infected-T cell in severe hepatitis caused by primary Epstein-Barr virus infection. Journal of Clinical Virology. ,vol. 35, pp. 250- 256 ,(2006) , 10.1016/J.JCV.2005.07.009
Diamantis P. Kofteridis, Mairi Koulentaki, Antonios Valachis, Maria Christofaki, Elias Mazokopakis, George Papazoglou, George Samonis, Epstein Barr Virus hepatitis European Journal of Internal Medicine. ,vol. 22, pp. 73- 76 ,(2011) , 10.1016/J.EJIM.2010.07.016
Li-Wei Gao, Zheng-De Xie, Ya-Yi Liu, Yan Wang, Kun-Ling Shen, Epidemiologic and clinical characteristics of infectious mononucleosis associated with Epstein-Barr virus infection in children in Beijing, China. World Journal of Pediatrics. ,vol. 7, pp. 45- 49 ,(2011) , 10.1007/S12519-011-0244-1
Nadine Harrison, Stuart Reid, Margaret Conacher, Jill Douglas, Anthony J. Swerdlow, Dorothy H. Crawford, Karen F. Macsween, Craig D. Higgins, Ranjit Thomas, Karen McAulay, Hilary Williams, A Cohort Study among University Students: Identification of Risk Factors for Epstein-Barr Virus Seroconversion and Infectious Mononucleosis Clinical Infectious Diseases. ,vol. 43, pp. 276- 282 ,(2006) , 10.1086/505400