Interpretive disparity among pathologists in breastsentinel lymph node evaluation

摘要: Abstract Background Immunohistochemical staining on breast sentinel lymph nodes (SLN) is controversial. Methods Twenty-five SLN cases were reviewed by 10 pathologists (three academic, seven private) including 5 negative both hematoxylin and eosin (HE 80% of positive IHC had at least one pathologist score it incorrectly. As tumor cells decrease in number, incorrect responses increase. When numbered less than 10, more 30% answered Conclusions number pathologists' ability to recognize them decreases. We propose adding “indeterminate” “positive” “negative” when 10.