Influence of the olfactory placode on the development of the brain in Xenopus laevis (Daudin): I. Axonal growth and connections of the transplanted olfactory placode

摘要: Abstract The olfactory placode of Xenopus laevis larvae at different stages development has been removed and transplanted onto the head host to determine effect donor/host age on viability transplant. Viability transplant (defined as penetration nerve in host's CNS) found be maximal when both donor were about stage29/30. Using stage 29/30 larvae, three distinct zones have mapped from which consistently sent its regions brain, namely telencephalon, diencephalon myelencephalon, respectively. additional input induced a hypertrophy where it penetrated telencephalon. When marked hyperplasia neuronal elements formation glomeruli was observed dorsal thalamus. There no overall change organization myelencephalon reached this region. Donors up including 41 remade placode. Removal after resulted permanent loss organ hypoplasia bulb results illustrate unique property sensory neurons induce anomalous CNS determine, these regions, characteristic terminal structures are commonly described glomeruli.