Preparation of a clickable monomer compatible with automated PNA synthesis
作者： Jean-Luc Montchamp , Axel Sabourin , Grace E. Newell
DOI: 10.1016/J.TETLET.2021.152987
关键词:
摘要: Abstract A propargyl-containing Fmoc-protected thymine monomer was synthesized for possible use in the pre- or post-functionalization of PNA oligomers via click chemistry. The should be suitable incorporation normal automated solid phase synthesis. synthesis is preparation gram-quantities monomers and uses reductive amination as key step.
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