Chikungunya virus and its mosquito vectors.

作者: Stephen Higgs , Dana Vanlandingham

DOI: 10.1089/VBZ.2014.1745

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摘要: Abstract Chikungunya virus (CHIKV), a mosquito-borne alphavirus of increasing public health significance, has caused large epidemics in Africa and the Indian Ocean basin; now it is spreading throughout Americas. The primary vectors CHIKV are Aedes (Ae.) aegypti and, after introduction mutation E1 envelope protein gene, highly anthropophilic geographically widespread Ae. albopictus mosquito. We review here research efforts to characterize viral genetic basis mosquito–vector interactions, use RNA interference other strategies for control mosquitoes, potentiation infection by mosquito saliva. Over past decade, emerged on truly global scale. Since 2013, transmission been reported Caribbean region, North America, Central South American countries, including Brazil, Columbia, Costa Rica, El Salvador, French Guiana, Guatemala, Guyana, Nicaragua, Panama, Suriname, Venezuela. ...

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