Human decidua synthesizes placental protein 14 (PP 14) in vitro

摘要: Human decidua was found to synthesize and secrete placental protein 14 (PP14). The presence of PP14 in tissue explants decidua, foetal membranes placenta from term pregnancy demonstrated by radioimmunoassay. content (1300 +/- 410 ng/100 mg tissue) higher than chorion (570 120 mg; P less 0.01), amnion (240 100 0.001) or (300 130 0.001). Three 36 times more released into culture medium decidual compared with the other tissues, cycloheximide decreased this release 39%. Placental tissues hardly any PP14. Decidual synthesis incorporation [35S]methionine immunoprecipitable culture.