The Use of Positron Emission Tomography in the Surgical Treatment of Epilepsy

作者: J. Engel , L. D. Cahan , W. W. Sutherling , P. H. Crandall , M. E. Phelps

DOI: 10.1007/978-3-642-71103-9_23

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摘要: The presurgical evaluation of epileptic patients who are candidates for resection an epileptogenic lesion is aimed at localizing abnormal area the brain that most responsible generating patient’s habitual seizures. Traditional methods identifying this region have depended heavily on interictal and ictal EEG recordings obtained using a variety techniques (Ajmone-Marsan 1980; Engel et al. 1983; Gloor 1975). Whether investigations concentrate spike activity, usually recorded chronically with extracranial electrodes, during intraoperative electrocorticography; or whether localization derived from invasive chronic procedures insert depth electrodes directly into (SEEG), over cortical surface, conclusions must be drawn identification epileptiform events propagate widely. Consequently, it impossible to certain site which occur reflects actual lesion, propagated activity distant beyond recording range available electrodes. False occurs in 10%–20% based scalp sphenoidal recordings, as well SEEG (Engel 1981; 1984; Lieb 1981 a, b). It difficult determine incidence false electrode onset since, when found, single important criterion resective surgery, rarely would surgical undertaken distance depth-recorded Crandall 1983). Nevertheless, series do not benefit may taken evi-dence technique.

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