Comparing central nervous system (CNS) and extra-CNS hemangiopericytomas in the Surveillance, Epidemiology, and End Results program: analysis of 655 patients and review of current literature.

摘要: BACKGROUND: Hemangiopericytomas (HPCs) are rare tumors in the central nervous system (CNS) and extra-CNS sites. The authors of this report used Surveillance, Epidemiology, End Results (SEER) Program to study prognostic factors patients with HPC. METHODS: SEER database was analyzed for who were diagnosed HPC from 1973 2007. Patients stratified into CNS groups. Univariate multivariate analyses performed overall survival (OS) endpoint using major demographic (age, race, sex) disease (tumor site). RESULTS: In total, 655 a group (n ¼ 199) an 456). statistically older (mean age, 53 years vs 49 years; P .008) more likely have larger (median greatest dimension, 7.0 cm 5.2 cm; < .001). had better OS cause-specific (CSS) compared (P .001 both). Negative predictors on analysis included tumor site (hazard ratio [HR], 1.6; .005) age (ages 40-59 years: HR, 2.08; .032; ages 60-79 3.9; .001; aged � 80 7.7; CONCLUSIONS: current demonstrated that HPCs worse CSS than HPCs. Cancer 2012;118:5331-8. V C 2012 American Society.