Technology-Enabled Clinical Trials: Transforming Medical Evidence Generation.

作者: Guillaume Marquis-Gravel , Matthew T. Roe , Mintu P. Turakhia , William Boden , Robert Temple

DOI: 10.1161/CIRCULATIONAHA.119.040798

关键词:

摘要: The complexity and costs associated with traditional randomized, controlled trials have increased exponentially over time, now threaten to stifle the development of new drugs devices. Never...

参考文章(42)
Sunil V. Rao, Connie N. Hess, Britt Barham, Laura H. Aberle, Kevin J. Anstrom, Tejan B. Patel, Jesse P. Jorgensen, Ernest L. Mazzaferri, Sanjit S. Jolly, Alice Jacobs, L. Kristin Newby, C. Michael Gibson, David F. Kong, Roxana Mehran, Ron Waksman, Ian C. Gilchrist, Brian J. McCourt, John C. Messenger, Eric D. Peterson, Robert A. Harrington, Mitchell W. Krucoff, A Registry-Based Randomized Trial Comparing Radial and Femoral Approaches in Women Undergoing Percutaneous Coronary Intervention JACC: Cardiovascular Interventions. ,vol. 7, pp. 857- 867 ,(2014) , 10.1016/J.JCIN.2014.04.007
L. D'Avolio, R. Ferguson, S. Goryachev, P. Woods, T. Sabin, J. O'Neil, C. Conrad, J. Gillon, J. Escalera, M. Brophy, P. Lavori, L. Fiore, Implementation of the Department of Veterans Affairs' first point-of-care clinical trial. Journal of the American Medical Informatics Association. ,vol. 19, ,(2012) , 10.1136/AMIAJNL-2011-000623
Kirsty Loudon, Shaun Treweek, Frank Sullivan, Peter Donnan, Kevin E Thorpe, Merrick Zwarenstein, None, The PRECIS-2 tool: designing trials that are fit for purpose BMJ. ,vol. 350, ,(2015) , 10.1136/BMJ.H2147
Adrian F. Hernandez, Rachael L. Fleurence, Russell L. Rothman, The ADAPTABLE Trial and PCORnet: Shining Light on a New Research Paradigm Annals of Internal Medicine. ,vol. 163, pp. 635- 636 ,(2015) , 10.7326/M15-1460
Nathan G. Cortez, I. Glenn Cohen, Aaron S. Kesselheim, FDA regulation of mobile health technologies The New England Journal of Medicine. ,vol. 371, pp. 372- 379 ,(2014) , 10.1056/NEJMHLE1403384
Elizabeth M Hill, Emma L Turner, Richard M Martin, Jenny L Donovan, "Let's get the best quality research we can": public awareness and acceptance of consent to use existing data in health research: a systematic review and qualitative study. BMC Medical Research Methodology. ,vol. 13, pp. 72- 72 ,(2013) , 10.1186/1471-2288-13-72
Stefan James, Sunil V. Rao, Christopher B. Granger, Registry-based randomized clinical trials—a new clinical trial paradigm Nature Reviews Cardiology. ,vol. 12, pp. 312- 316 ,(2015) , 10.1038/NRCARDIO.2015.33
Eric J. Topol, Steven R. Steinhubl, Ali Torkamani, Digital Medical Tools and Sensors JAMA. ,vol. 313, pp. 353- 354 ,(2015) , 10.1001/JAMA.2014.17125
Ole Fröbert, Bo Lagerqvist, Göran K. Olivecrona, Elmir Omerovic, Thorarinn Gudnason, Michael Maeng, Mikael Aasa, Oskar Angerås, Fredrik Calais, Mikael Danielewicz, David Erlinge, Lars Hellsten, Ulf Jensen, Agneta C. Johansson, Amra Kåregren, Johan Nilsson, Lotta Robertson, Lennart Sandhall, Iwar Sjögren, Ollie Östlund, Jan Harnek, Stefan K. James, Thrombus aspiration during ST-segment elevation myocardial infarction. The New England Journal of Medicine. ,vol. 369, pp. 1587- 1597 ,(2013) , 10.1056/NEJMOA1308789
Michael J. Noto, Henry J. Domenico, Daniel W. Byrne, Tom Talbot, Todd W. Rice, Gordon R. Bernard, Arthur P. Wheeler, Chlorhexidine Bathing and Health Care–Associated Infections: A Randomized Clinical Trial JAMA. ,vol. 313, pp. 369- 378 ,(2015) , 10.1001/JAMA.2014.18400