National audit of antidote stocking in acute hospitals in the UK

摘要: Background Inadequate stocking of essential antidotes in hospitals for the treatment poisoned patients has been reported worldwide. Joint National Poisons Information Service (NPIS)/College Emergency Medicine (CEM) guidelines antidote UK emergency departments and acute were published 2008. Aim To determine impact these by surveying availability UK. Methods A two-page questionnaire consisting information was distributed 2010 to Chief Pharmacist all The 28 NPIS/CEM as well that Intralipid surveyed. Results Surveys completed 196 224 (87.5%) hospitals. Over 90% had acetylcysteine, activated charcoal, dantrolene, desferrioxamine, naloxone, flumazenil vitamin K available within recommended time period. Pralidoxime be held only 33% hospitals, though pralidoxime is supplied Department Health 95 act holding centres. Cyproheptadine viper venom antiserum around 50% For cyanide toxic alcohol poisoning, more than one available. most at least (usually dicobalt edetate) but 9 (5%) none four antidotes. glycol ethanol intravenous use not fomepizole 30 (15%) did stock any poisoning. Conclusion Stocking less commonly used inconsistent. This likely result delayed access worse patient outcomes.