High-level vancomycin-resistant enterococci causing hospital infections

摘要: Nosocomial infection or colonization due to enterococci with high-level resistance vancomycin (minimal inhibitory concentrations [MICs] between 64 and greater than 2000 mg/L) has occurred in 41 patients renal disease. These vancomycin-resistant were cultured from many sources including blood. All but one strain contained more plasmids ranging molecular weight 1.0 40 Megadaltons (MDa). Vancomycin was transferable by conjugation a susceptible recipient of Enterococcus faecalis this not always associated plasmid DNA. The emergence causing significant clinical infections is particular importance since widely regarded as reserve drug for the management multi-resistant Gram-positive organisms.