Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy

摘要: Eighty-six children with non-Hodgkin's lymphoma were studied from 1964 to January 31, 1975. Seventy-six percent of the 43 patients in nonprotocol group had far advanced disease, and 76% Rappaport's diffuse histology. Only 11% these survived free disease. The second received LSA2L2 protocol. disease 86% Of are surviving a median observation time 25+ months. Fifty-one survivors off therapy without evidence Prognostic factors such as primary sites, stages, histology, others discussed. most important prognostic factor is early aggressive therapy, achievement complete response status within 1-2 months onset therapy.