Formation of prostacyclin-sensitive platelet aggregates in human whole blood in vitro. Part II. The occurrence of the phenomenon in males suffering from acute myocardial infarction

作者: B. Spławinska , W. Furmaga , J. Kuzniar , M. Stawiarski , I. Pikor

DOI: 10.1080/00365518709168880

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摘要: The de-aggregatory effect of prostacyclin (PGI2) and the rate spontaneous platelet aggregation (SPA) were studied in vitro whole blood 24 males with acute myocardial infarction (MI) 18 males, patient controls (PC). PGI2 SPA (measured as a percentage changes free number blood) higher (p<0.01) MI than PC. was (p<0.05) on first day 14 following MI. highest found patients complicated by ventricular fibrillation. In neither groups did correlate patients' age, haematocrit, erythrocyte leucocyte counts, triglycerides, HDL, LDL or total cholesterol levels. group, correlated concentration (r=-0.59, p<0.05), elevation glutamic oxalacetic transaminase (r=0.53, p<0.05) cr...

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