From cell population models to tumor control probability: Including cell cycle effects
作者： Thomas Hillen , Gerda de Vries , Jiafen Gong , Chris Finlay
DOI: 10.3109/02841861003631487
关键词:
摘要: AbstractBackground. Classical expressions for the tumor control probability (TCP) are based on models survival fraction of cancer cells after radiation treatment. We focus derivation TCP from dynamic cell population models. In particular, we derive a formula generalized model that includes cycle by considering compartment actively proliferating and quiescent cells, with being less sensitive to than cells. Methods. generalize previously derived formulas Zaider Minerbo Dawson Hillen our model. then use six prostate treatment protocols as case study show how works affects Results. The Zaider-Minerbo Dawson-Hillen special cases presented here. former one represents t...
informahealthcare.com
ualberta.ca 参考文章(39)
Kristin R. Swanson, Lawrence D. True, Daniel W. Lin, Kent R. Buhler, Robert Vessella, James D. Murray, A Quantitative Model for the Dynamics of Serum Prostate-Specific Antigen as a Marker for Cancerous Growth: An Explanation for a Medical Anomaly American Journal of Pathology. ,vol. 158, pp. 2195- 2199 ,(2001) , 10.1016/S0002-9440(10)64691-3
David J Carlson, Robert D Stewart, X Allen Li, Kristofer Jennings, Jian Z Wang, M Guerrero, Comparison of in vitro and in vivo α/β ratios for prostate cancer Physics in Medicine and Biology. ,vol. 49, pp. 4477- 4491 ,(2004) , 10.1088/0031-9155/49/19/003
H. P. Leenhouts, K. H. Chadwick, The Molecular Theory of Radiation Biology ,(1981)
David M. Prescott, Abraham S. Flexer, Cancer, the misguided cell ,(1981)
P Stavrev, N Stavreva, A Niemierko, M Goitein, Generalization of a model of tissue response to radiation based on the idea of functional subunits and binomial statistics. Physics in Medicine and Biology. ,vol. 46, pp. 1501- 1518 ,(2001) , 10.1088/0031-9155/46/5/312
John F. Fowler, The linear-quadratic formula and progress in fractionated radiotherapy British Journal of Radiology. ,vol. 62, pp. 679- 694 ,(1989) , 10.1259/0007-1285-62-740-679
Minaya Villasana, Ami Radunskaya, A delay differential equation model for tumor growth Journal of Mathematical Biology. ,vol. 47, pp. 270- 294 ,(2003) , 10.1007/S00285-003-0211-0
H.D. Thames, S.M. Bentzen, I. Turesson, M. Overgaard, W. Van den Bogaert, Time-dose factors in radiotherapy: a review of the human data Radiotherapy and Oncology. ,vol. 19, pp. 219- 235 ,(1990) , 10.1016/0167-8140(90)90149-Q
M Zaider, G N Minerbo, Tumour control probability: a formulation applicable to any temporal protocol of dose delivery Physics in Medicine and Biology. ,vol. 45, pp. 279- 293 ,(2000) , 10.1088/0031-9155/45/2/303
Elizabeth L. Travis, Susan L. Tucker, ISOEFFECT MODELS AND FRACTIONATED RADIATION THERAPY International Journal of Radiation Oncology Biology Physics. ,vol. 13, pp. 283- 287 ,(1987) , 10.1016/0360-3016(87)90141-6