Detection of Chemically Induced Y-Chromosomal Nondisjunction in Human Spermatozoa
作者： Marvin S. Legator , Robert W. Kapp
DOI: 10.1007/978-1-4684-4664-7_11
关键词:
摘要: In the area of chemical mutagenesis certain procedures seem to gain considerable popularity even though their relevance identifying human hazards is questionable or genetic basis for tests has yet be established. Conversely, there are where potential lesions in relevant systems considerable, but utilization slow develop. A procedure with great mutagens that induce cytogenetic changes man detection chemically induced increase Y chromosomes sperm. This procedure, utilizing fluorochromes, may one more important developments recent years field mutagenesis. The amount data, however, and presumably number investigators evaluating this technique minimal. chapter, we will describe studies led development method, discuss technique, present data obtained using procedure.
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sci-hub.st 参考文章(11)
Havelock Thompson, John Melnyk, Frederick Hecht, REPRODUCTION AND MEIOSIS IN XYY The Lancet. ,vol. 290, pp. 831- ,(1967) , 10.1016/S0140-6736(67)92263-5
R.A. Beatty, F-bodies as Y chromosome markers in mature human sperm heads: a quantitative approach Cytogenetic and Genome Research. ,vol. 18, pp. 33- 49 ,(1977) , 10.1159/000130746
PETER BARLOW, C. G. VOSA, The Y Chromosome in Human Spermatozoa Nature. ,vol. 226, pp. 961- 962 ,(1970) , 10.1038/226961A0
Robert W. Kapp, Dante J. Picciano, Cecil B. Jacobson, Y-chromosomal nondisjunction in dibromochloropropane-exposed workmen Mutation Research\/environmental Mutagenesis and Related Subjects. ,vol. 64, pp. 47- 51 ,(1979) , 10.1016/0165-1161(79)90136-5
R. W. Kapp, C. B. Jacobson, Analysis of human spermatozoa for Y chromosomal nondisjunction Teratogenesis Carcinogenesis and Mutagenesis. ,vol. 1, pp. 193- 211 ,(1981) , 10.1002/TCM.1770010208
T. Caspersson, S. Farber, G.E. Foley, J. Kudynowski, E.J. Modest, E. Simonsson, U. Wagh, L. Zech, Chemical differentiation along metaphase chromosomes Experimental Cell Research. ,vol. 49, pp. 219- 222 ,(1968) , 10.1016/0014-4827(68)90538-7
T. Caspersson, M. Hultén, J. Lindsten, L. Zech, Distinction between extra G-like chromosomes by quinacrine mustard fluorescence analysis Experimental Cell Research. ,vol. 63, pp. 240- 243 ,(1970) , 10.1016/0014-4827(70)90363-0
A. T. SUMNER, JACQUELINE A. ROBINSON, H. J. EVANS, Distinguishing between X Y and YY-bearing human spermatozoa by fluorescence and DNA content. Nature. ,vol. 229, pp. 231- 233 ,(1971) , 10.1038/NEWBIO229231A0
R W Kapp, Detection of aneuploidy in human sperm. Environmental Health Perspectives. ,vol. 31, pp. 27- 31 ,(1979) , 10.1289/EHP.793127
A. T. Sumner, J. A. Robinson, A difference in dry mass between the heads of X- and Y-bearing human spermatozoa Reproduction. ,vol. 48, pp. 9- 15 ,(1976) , 10.1530/JRF.0.0480009