An Empirical Study of Phosphine Ligands for the Methoxycarbonylation of Medium-Chain Alkenes

摘要: The methoxycarbonylation reaction provides a route to the synthesis of esters from medium-chain alkenes that may be used as fuel supplements. However, known productive catalytic systems are expensive and/or unstable at elevated temperatures. Most data available on is derived ethylene and styrene substrates. To broaden scope, we conducted comparative study range phosphine ligands under comparable conditions for 1-octene. results demonstrate number ligand structural motifs facilitate process effectually. Furthermore, critical importance alkene isomerization acid/ligand Pd/ligand ratios presented.