The relative amounts of long-chain acylcarnitine, acetylcarnitine, and free carnitine in organs of rats in different nutritional states and with alloxan diabetes

作者: Thomas Bøhmer , Kaare R. Norum , Jon Bremer

DOI: 10.1016/0005-2760(66)90066-X

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摘要: Abstract 1. The relative amounts of free carnitine, acetylcarnitine, and long-chain acylcarnitines have been investigated in the heart, liver kidney male rats during different nutritional states with alloxan diabetes. 2. proportion to carnitine increases fat-feeding, diabetes fasting, decreases when glucose is given again. 3. level changes same direction as acyl-CoA's which known alter these conditions. 4. In acetylcarnitine again consumed. These are accord occur acetyl-CoA similar heart were not significant. 5. method described seems be convenient for studying activated fatty acids tissues.

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