C-Reactive Protein to Serum Albumin Ratio Is an Independent Predictor of All-Cause Mortality in Patients with ANCA-Associated Vasculitis

作者: Jae-Seung Moon , Sung Soo Ahn , Yong-Beom Park , Sang-Kyou Lee , Sang-Won Lee

DOI: 10.3349/YMJ.2018.59.7.865

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摘要: PURPOSE We investigated whether C-reactive protein (CRP) to serum albumin ratio (CAR) could be an independent predictor of all-cause mortality in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). MATERIALS AND METHODS retrospectively reviewed the medical records 170 AAV. collected clinical and laboratory data. also examined AAV-related traditional risk factors mortality. To assess hazard ratios variables, we performed univariable multivariable Cox model analyses. RESULTS The mean age was 55.0 years 53 (31.2%) were male among AAV (88 microscopic polyangiitis, 43 granulomatosis 39 eosinophilic polyangiitis). ANCA detected 129 (75.9%). initial CRP 41.1 (mg/L) 3.6 (g/dL), CAR at diagnosis 14.8. most common factor hypertension (42.4%), followed by chronic kidney disease ≥stage 3 (25.9%). Fourteen (8.2%) died during follow-up 56.7 months. In both analyses, identified as comparable diabetes mellitus (DM). Moreover, ≥10.35 having DM exhibited a higher frequency than those without. CONCLUSION can mortality, DM, conventional

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