The Novel Histologic International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification System of Lung Adenocarcinoma Is a Stage-Independent Predictor of Survival
作者： Arne Warth , Thomas Muley , Michael Meister , Albrecht Stenzinger , Michael Thomas
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摘要: Purpose Our aim was to analyze and validate the prognostic impact of novel International Association for Study Lung Cancer (IASLC)/American Thoracic Society (ATS)/European Respiratory (ERS) proposal an architectural classification invasive pulmonary adenocarcinomas (ADCs) across all tumor stages. Patients Methods The pattern a large cohort 500 patients with resected ADCs (stages I IV) retrospectively analyzed in 5% increments classified according their predominant architecture (lepidic, acinar, solid, papillary, or micropapillary), as proposed by IASLC/ATS/ERS. Subsequently, histomorphologic data were correlated clinical data, adjuvant therapy, patient outcome. Results Overall survival differed significantly between lepidic (78.5 months), acinar (67.3 solid (58.1 papillary (48.9 micropapillary (44.9 months) (P = .007). When patterns lumped into groups, this resulted even mor...
sci-hub.se 参考文章(26)
Sandra C Tomaszek, Marianne Huebner, Dennis A Wigle, Prospects for molecular staging of non-small-cell lung cancer from genomic alterations Expert Review of Respiratory Medicine. ,vol. 4, pp. 499- 508 ,(2010) , 10.1586/ERS.10.40
Corey J. Langer, Benjamin Besse, Antonio Gualberto, Elizabeth Brambilla, Jean-Charles Soria, The Evolving Role of Histology in the Management of Advanced Non–Small-Cell Lung Cancer Journal of Clinical Oncology. ,vol. 28, pp. 5311- 5320 ,(2010) , 10.1200/JCO.2010.28.8126
S Aida, H Shimazaki, K Sato, M Sato, H Deguchi, Y Ozeki, S Tamai, Prognostic analysis of pulmonary adenocarcinoma subclassification with special consideration of papillary and bronchioloalveolar types Histopathology. ,vol. 45, pp. 468- 476 ,(2004) , 10.1111/J.1365-2559.2004.01946.X
Masayuki Noguchi, Akio Morikawa, Masanori Kawasaki, Yoshihiro Matsuno, Tesshi Yamada, Setsuo Hirohashi, Haruhiko Kondo, Yukio Shimosato, Small adenocarcinoma of the lung. Histologic characteristics and prognosis Cancer. ,vol. 75, pp. 2844- 2852 ,(1995) , 10.1002/1097-0142(19950615)75:12<2844::AID-CNCR2820751209>3.0.CO;2-#
Donald F. Gleason, George T. Mellinger, , Prediction of Prognosis for Prostatic Adenocarcinoma by Combined Histological Grading and Clinical Staging The Journal of Urology. ,vol. 111, pp. 58- 64 ,(1974) , 10.1016/J.JURO.2016.10.099
Joon Yim, Lee-Ching Zhu, Luis Chiriboga, Heather N Watson, Judith D Goldberg, Andre L Moreira, Histologic features are important prognostic indicators in early stages lung adenocarcinomas. Modern Pathology. ,vol. 20, pp. 233- 241 ,(2007) , 10.1038/MODPATHOL.3800734
Marc Riquet, Christophe Foucault, Pascal Berna, Jalal Assouad, Antoine Dujon, Claire Danel, Prognostic value of histology in resected lung cancer with emphasis on the relevance of the adenocarcinoma subtyping. The Annals of Thoracic Surgery. ,vol. 81, pp. 1988- 1995 ,(2006) , 10.1016/J.ATHORACSUR.2006.01.021
Akihiko Yoshizawa, Noriko Motoi, Gregory J Riely, Cami S Sima, William L Gerald, Mark G Kris, Bernard J Park, Valerie W Rusch, William D Travis, Impact of proposed IASLC/ATS/ERS classification of lung adenocarcinoma: prognostic subgroups and implications for further revision of staging based on analysis of 514 stage I cases Modern Pathology. ,vol. 24, pp. 653- 664 ,(2011) , 10.1038/MODPATHOL.2010.232
Vincent A. Miller, Fred R. Hirsch, David H. Johnson, Systemic Therapy of Advanced Bronchioloalveolar Cell Carcinoma: Challenges and Opportunities Journal of Clinical Oncology. ,vol. 23, pp. 3288- 3293 ,(2005) , 10.1200/JCO.2005.19.240
Alain C. Borczuk, Fang Qian, Angeliki Kazeros, Jennifer Eleazar, Adel Assaad, Joshua R. Sonett, Mark Ginsburg, Lyall Gorenstein, Charles A. Powell, Invasive size is an independent predictor of survival in pulmonary adenocarcinoma. The American Journal of Surgical Pathology. ,vol. 33, pp. 462- 469 ,(2009) , 10.1097/PAS.0B013E318190157C