Persistent interferon-ß-1b-induced psychosis in a patient with multiple sclerosis.

作者: Giovanni Manfredi , Giorgio D. Kotzalidis , Gabriele Sani , Alexia E. Koukopoulos , Valeria Savoja

DOI: 10.1111/J.1440-1819.2010.02122.X

关键词:

摘要: Interferon-s is used in patients with multiple sclerosis to reduce autoimmunity; although other psychiatric side-effects are common, contrast interferon-alpha, psychosis has been reported only once. A patient developed auditory hallucinations, paranoid delusions, and increased aggressiveness after 16 months of treatment interferon-s-1b, 250 mg every day. He responded about one month antipsychotic treatment, but tended relapse upon dose reduction, 2 years still needs antipsychotics control his symptoms. Because there was no change magnetic resonance imaging between pre- post-treatment interferon, we concluded that more related interferon than the underlying disease.

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