Spatial auditory regularity encoding and prediction: Human middle-latency and long-latency auditory evoked potentials.

摘要: Abstract By encoding acoustic regularities present in the environment, human brain can generate predictions of what is likely to occur next. Recent studies suggest that deviations from encoded are detected within 10–50 ms after stimulus onset, as indicated by electrophysiological effects middle latency response (MLR) range. This upstream previously known long-latency (LLR) signatures deviance detection such mismatch negativity (MMN) component. In study, we created predictable and unpredictable contexts investigate MLR LLR spatial auditory generation these regularities. Chirps were monaurally delivered an either regular (predictable: left–right–left–right) or a random (unpredictable left/right alternation repetition) manner. Occasional omissions occurred both types sequences. Results showed Na component (peaking at 34 ms onset) was attenuated for relative chirps, albeit no differences observed omission responses same range, larger chirp-and omission-evoked elicited than condition, predictability more prominent over right hemisphere. We discuss our findings framework hierarchical organization regularity encoding. article part Special Issue entitled SI: Prediction Attention.