Inhibition of cisplatin-induced vomiting by selective 5-hydroxytryptamine M-receptor antagonism
作者： Wesley D. Miner , Gareth J. Sanger
DOI: 10.1111/J.1476-5381.1986.TB10228.X
关键词:
摘要: MDL 72222, the selective 5-hydroxytryptamine (5-HT) M-receptor antagonist, prevented or reduced cisplatin-induced emesis in ferrets. It is suggested that cisplatin-induced, and possibly other cytotoxic drug-induced vomiting may involve a 5-HT mechanism.
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