Supratentorial gliomas: a comparative study by grade and histologic type.

作者: Edward G. Shaw , Bernd W. Scheithauer , Judith R. O'Fallon

DOI: 10.1023/A:1005715703598

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摘要: Purpose: To try and identify biologic differences based on tumor grade histologic type between the major classes of glial tumors, including low-grade diffuse fibrillary andpilocytic astrocytomas, oligodendrogliomas, mixed oligo-astrocytomas, andhigh-grade oligo-astrocytomas.Methods: Utilizing St. Anne-Mayo (SAM) grading system, incidence, patient characteristics, survivals 196 patientswith (SAM 1 + 2) 318 patients with high-grade(SAM 3 4) supratentorial tumors were compared.Results: Among most favorable 5- 10-year survival rates for pilocytic astrocytomas,which 85% 79%, respectively. Median survivaland other lower, proportionately improved by presenceof an oligodendroglial component: astrocytomas — 4.7 years, 46%, 17%; oligodendroglioma 9.8 73%, 49%; oligo-astrocytoma 7.1 63%, 33%, For high-grade either oligodendrogliomas or oligo-astrocytomas had comparablefavorable in comparison to astrocytomas.Median 4.5 45%, 15% versus 0.8 3%, 0% forthe respectively.Conclusion: These data suggest that both gliomas have outcomes which are highly dependent upon type.

参考文章(19)
Sverre J. Mørk, Karl-Fredrik Lindegaard, Tore B. Halvorsen, Egil H. Lehmann, Torfinn Solgaard, Reidulv Hatlevoll, Sverre Harvei, Jeremy Ganz, Oligodendroglioma: incidence and biological behavior in a defined population Journal of Neurosurgery. ,vol. 63, pp. 881- 889 ,(1985) , 10.3171/JNS.1985.63.6.0881
Paul W. Scanlon, William F. Taylor, Radiotherapy of Intracranial Astrocytomas Neurosurgery. ,vol. 5, pp. 301- 308 ,(1979) , 10.1227/00006123-197909000-00001
J. Gregory Cairncross, David R. Macdonald, Successful chemotherapy for recurrent malignant oligodendroglioma Annals of Neurology. ,vol. 23, pp. 360- 364 ,(1988) , 10.1002/ANA.410230408
Catherine Daumas-Duport, Bernd Scheithauer, Judith O'Fallon, Patrick Kelly, Grading of astrocytomas: A simple and reproducible method Cancer. ,vol. 62, pp. 2152- 2165 ,(1988) , 10.1002/1097-0142(19881115)62:10<2152::AID-CNCR2820621015>3.0.CO;2-T
Gerald W. Marsa, Don R. Goffinet, Lucien J. Rubinstein, Malcolm A. Bagshaw, Megavoltage irradiation in the treatment of gliomas of the brain and spinal cord Cancer. ,vol. 36, pp. 1681- 1689 ,(1975) , 10.1002/1097-0142(197511)36:5<1681::AID-CNCR2820360523>3.0.CO;2-Z
Edward G. Shaw, Catherine Daumas-Duport, Bernd W. Scheithauer, David T. Gilbertson, Judith R. O'Fallon, John D. Earle, Edward R. Laws, Haruo Okazaki, Radiation therapy in the management of low-grade supratentorial astrocytomas Journal of Neurosurgery. ,vol. 70, pp. 853- 861 ,(1989) , 10.3171/JNS.1989.70.6.0853
Edward G. Shaw, Bernd W. Scheithauer, Judith R. O'Fallon, Henry D. Tazelaar, Dudley H. Davis, Oligodendrogliomas: the Mayo Clinic experience. Journal of Neurosurgery. ,vol. 76, pp. 428- 434 ,(1992) , 10.3171/JNS.1992.76.3.0428
A.C. Whitton, H.G.G. Bloom, Low grade glioma of the cerebral hemispheres in adults: a retrospective analysis of 88 cases International Journal of Radiation Oncology*Biology*Physics. ,vol. 18, pp. 783- 786 ,(1990) , 10.1016/0360-3016(90)90397-3
J W Kernohan, R F Mabon, A simplified classification of the gliomas. Proceedings of the staff meetings. Mayo Clinic. ,vol. 24, pp. 71- 75 ,(1949)
Jaskólsky D, Papierz W, Kotwica Z, Zawirski M, Mixed gliomas. Their clinical course and results of surgery. Zentralblatt für Neurochirurgie. ,vol. 48, pp. 120- ,(1987)