Redesign of the coenzyme specificity of a dehydrogenase by protein engineering
作者： Nigel S. Scrutton , Alan Berry , Richard N. Perham
DOI: 10.1038/343038A0
关键词:
摘要: Directed mutagenesis and molecular modelling have been used to identify a set of amino-acid side chains in glutathione reductase that confer specificity for the coenzyme NADP + . …
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