A light-responsive, self-immolative linker for controlled drug delivery via peptide- and protein-drug conjugates
作者： Chuanlong Zang , Huawei Wang , Tiantian Li , Yingqian Zhang , Jiahui Li
DOI: 10.1039/C9SC03016F
关键词:
摘要: Photoirradiation of the PC4AP linker generates an active intermediate that reacts intramolecularly with a primary amine on the carrier peptide/protein, leading to rapid release of the drug without generating any toxic side products.
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