Chemotaxonomy of Penicillium aurantiogriseum and related species

摘要: Penicillium aurantiogriseum sensu lato is the most common cereal-borne species of worldwide occurrence and it has a complex taxonomy. A total 519 isolates, including NRRL cultures used by Raper & Thom (1949) in their P. cyclopium, viridicatum ochraceum series, was examined for expressions differentiation, especially secondary metabolites. The fungi were micromorphologically quite similar. Isolates previously allocated to cyclopium separated into nine based on biosynthetic families metabolites from several less conspicuous morphological physiological differences. accepted aurantiogriseum, aurantiovirens, freii, melanoconidium, neoechinulatum, polonicum, tricolor . These produced characteristic combinations following mycotoxins: xanthomegnin, viomellein, vioxanthin, penicillic acid, terrestric viridic verrucosidin, penitrem other metabolites: viridamine, aurantiamine, auranthine, verrucofortine, puberuline, cyclopeptin, dehydrocyclopeptin, cyclopenin, cyclopenol, 3-methoxyviridicatin, viridicatol, brevianamide B, meleagrin oxaline. All known could be standards liquid chromatography — diode array detection. Some isolates polonicum are produce nephrotoxic glycopeptides possibly associated with Balkan endemic nephropathy. It recommended that should identified level using combination morphological, metabolite data.