Audit of Antibiotic Prescribing Practices for Neonatal Sepsis and Measurement of Outcome in New Born Unit at Kenyatta National Hospital.

摘要: Background. Neonatal sepsis is a leading cause of morbidity and mortality globally. A high index suspicion required since features are nonspecific. Auditing antibiotic use necessary to reduce misuse minimise development resistance. Objectives. To assess the prescribing practices in NBU at KNH against recommended Kenyan guidelines for neonatal sepsis. In addition, outcome within 7 days was described. Methods. This prospective audit 320 neonates over 2-month period KNH. Data were collected using structured questionnaire, stored MS-EXCEL, analysed STATA. Results. Documentation perinatal risk factors clinical admission time change antibiotics very poor. The rate investigations confirm infection low. Blood cultures done only 13 (4%) on admission, while complete blood count C reactive protein 224 (70%) 198 (62%), respectively. Appropriate as per prescribed 313 (97.8%) admission. However, these not stopped 48-72 hours 148 (53.62%) who had improved. Overall 80 (25%). Majority (55%) died 48 hours. Mortality among preterm neonates; 70 (43.8%) out 160. Conclusion. documentation continuation inappropriate. especially first improve documentation, availability checklist recommended.