Prevention of rheumatic fever in Costa Rica.

摘要: During the beginning of 1970s, major changes occurred in Costa Rica treatment streptococcal throat infections. Because poor compliance with regimens using orally administered agents, intramuscular administration benzathine penicillin was selected as standard and cultures were eliminated a prerequisite for prescribing antibiotics. A decline incidence rheumatic fever then occurred. We believe that similar health intervention could be applied other developing countries.