Influences of localized aortic valve damage on coronary artery blood flow in acute aortic regurgitation: an experimental study.
作者： S Nakao , T Nagatomo , K Kiyonaga , T Kashima , H Tanaka
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摘要: We examined the influences of localized aortic valve damage on coronary artery blood flow and prognosis in acute regurgitation. Aortic regurgitation was produced 18 open-chest dogs by extensively cutting one three cusps with a nerve knife introduced via cardiac apex. The were separated into groups six each. In each group noncoronary cusp (NCC), right (RCC), or left (LCC) cut. ventricular pressures; phasic aortic, anterior descending (LAD), (RCA) flows; electrocardiograms simultaneously recorded before after production AR. All NCC RCC survived for at least 30 to 60 min, but all LCC died 5 9 min AR due failure. After 2 regurgitation, total, systolic, diastolic LAD flows 39 +/- 14, 19 9, 20 8 ml/min (mean SD) group, 41 15, 31 10 6 5, -10 respectively. corresponding RCA 15 6, 4 3 13 8, 21 12, -8 14 4, -5 1 respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
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