Tobacco sidestream smoke: uptake by nonsmokers.

作者: Dietrich Hoffmann , Nancy J. Haley , John D. Adams , Klaus D. Brunnemann

DOI: 10.1016/S0091-7435(84)80011-0

关键词:

摘要: Some epidemiological studies indicate an association between passive smoking and increased risk for cancer, especially cancer of the lung. Other reports, however, have failed to confirm these findings. Biochemical analyses physiological fluids markers exposure tobacco smoke are needed as measurements uptake components by nonsmokers estimation relative passively exposed persons compared with that active cigarette smokers. This communication reports carbon monoxide, hydrogen cyanide, nicotine after under controlled conditions. The results salivary values reflect level recent within hour urinary cotinine in preceding hours. N -Nitrosoproline has been shown serve indicator endogenous -nitrosamine formation smokers; yet, preliminary do not excretion -nitrosoproline is following short-term exposure. In infants, first field suggest a correlation tobacco-smoke-polluted environments levels continine both serum urine.

参考文章(14)
Susan Preston-Martin, Mimi C. Yu, Brian E. Henderson, Barbara Benton, N-Nitroso compounds and childhood brain tumors: a case-control study. Cancer Research. ,vol. 42, pp. 5240- 5245 ,(1982)
Klaus D. Brunnemann, Dietrich Hoffmann, Endogenous formation of N-nitrosoproline in cigarette smokers. Cancer Research. ,vol. 43, pp. 5570- 5574 ,(1983)
Geoffrey C. Kabat, Ernst L. Wynder, Lung cancer in nonsmokers Cancer. ,vol. 53, pp. 1214- 1221 ,(1984) , 10.1002/1097-0142(19840301)53:5<1214::AID-CNCR2820530532>3.0.CO;2-8
Takeshi Hirayama, PASSIVE SMOKING AND LUNG CANCER: CONSISTENCY OF ASSOCIATION The Lancet. ,vol. 322, pp. 1425- 1426 ,(1983) , 10.1016/S0140-6736(83)90960-1
Robert A. Greenberg, Nancy J. Haley, Ruth A. Etzel, Frank A. Loda, Measuring the Exposure of Infants to Tobacco Smoke New England Journal of Medicine. ,vol. 310, pp. 1075- 1078 ,(1984) , 10.1056/NEJM198404263101703
Dimitrios Trichopoulos, Anna Kalandidi, Loukas Sparros, Lung cancer and passive smoking: conclusion of Greek study. The Lancet. ,vol. 322, pp. 677- 678 ,(1983) , 10.1016/S0140-6736(83)92549-7
Dietrich Hoffmann, T.C. Tso, Gio B. Gori, The less harmful cigarette Preventive Medicine. ,vol. 9, pp. 287- 296 ,(1980) , 10.1016/0091-7435(80)90089-4
Helmut Bartsch, Hiroshi Ohshima, Quantitative estimation of endogenous nitrosation in humans by monitoring N-nitrosoproline excreted in the urine. Cancer Research. ,vol. 41, pp. 3658- 3662 ,(1981)