摘要: Bei den meisten Krankheiten ist das Therapieziel ahnlich. Es gilt, die subjektiven Beschwerden zu lindern, Progredienz einzudammen und mogliche Komplikationen auszuschalten. schubweisem Verlauf auch Rezidivprophylaxe von groster Bedeutung. Wahrend es bei banalen Erkrankungen genugt, Therapie rein nach der Symptomatik auszurichten, mussen potentiell gefahrlichen insbesondere malignen objektive Zeichen, wie v. a. Histologie als Richtlinien fur herangezogen werden.
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Bucher P, Blum Al, Sonnenberg A, Lepsien G, Course and prognosis of reflux disease under conservative and surgical treatment Schweizerische Medizinische Wochenschrift. ,vol. 108, pp. 2072- 2078 ,(1978)
P. Powell-Jackson, H. Barkley, T.C. Northfield, EFFECT OF CIMETIDINE IN SYMPTOMATIC GASTRO-ŒSOPHAGEAL REFLUX The Lancet. ,vol. 312, pp. 1068- 1069 ,(1978) , 10.1016/S0140-6736(78)91802-0
R. Siewert, F. Weiser, H.M. Jennewein, F. Waldeck, Clinical and Manometric Investigations of the Lower Esophageal Sphincter and its Reactivity to Pentagastrin in Patients with Hiatus Hernia Digestion. ,vol. 10, pp. 287- 297 ,(1974) , 10.1159/000197547
J. Behar, D. G. Sheahan, P. Biancani, H. M. Spiro, E. H. Storer, Medical and Surgical Management of Reflux Esophagitis New England Journal of Medicine. ,vol. 293, pp. 263- 268 ,(1975) , 10.1056/NEJM197508072930602
C. Stanciu, J. R. Bennett, Metoclopramide in gastrooesophageal reflux Gut. ,vol. 14, pp. 275- 279 ,(1973) , 10.1136/GUT.14.4.275
RAYMOND L. FARRELL, Cholinergic Therapy of Chronic Heartburn Annals of Internal Medicine. ,vol. 80, pp. 573- 576 ,(1974) , 10.7326/0003-4819-80-5-573
C STANCIU, ALGINATE/ANTACID IN THE REDUCTION OF GASTRO-ŒSOPHAGEAL REFLUX The Lancet. ,vol. 303, pp. 109- 111 ,(1974) , 10.1016/S0140-6736(74)92340-X
Amnon Sonnenberg, Gerd Lepsien, Stefan A. M�ller-Lissner, Hans R. Koelz, J. R�diger Siewert, Andr� L. Blum, When is esophagitis healed? esophageal endoscopy, histology and function before and after cimetidine treatment. Digestive Diseases and Sciences. ,vol. 27, pp. 297- 302 ,(1982) , 10.1007/BF01296747
E. Wesdorp, J. Bartelsman, K. Pape, W. Dekker, G.N. Tytgat, Oral cimetidine in reflux esophagitis: a double blind controlled trial. Gastroenterology. ,vol. 74, pp. 821- 824 ,(1978) , 10.1016/0016-5085(78)90133-6
Douglas L. Brand, Ivan R. Eastwood, Doris Martin, William B. Carter, Charles E. Pope, Esophageal symptoms, manometry, and histology before and after antireflux surgery: a long-term follow-up study. Gastroenterology. ,vol. 76, pp. 1393- 1401 ,(1979) , 10.1016/0016-5085(79)90407-4