作者: J. Rüschoff , T. Bocker , P. Vogel , J. Schlegel
DOI: 10.1007/978-3-642-80035-1_6
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摘要: Histological type, malignancy grade, and tumor stage are among the most important parameters predicting outcome in cancer patients Making use of immunocytochemistry as well polymerase chain reaction-based techniques demonstration micrometastatic spread, for example, into bone marrow, lymph nodes, peritoneal cavity, is a new staging parameter prognostic significance. In contrast, value different proliferation markers such Ki67 (Mib 1), PCNA, AgNOR has not yet been unequivocally established.