Comparative mapping of human alphoid satellite DNA repeat sequences in the great apes

作者: Rhea V. Samonte , K. H. Ramesh , Ram S. Verma

DOI: 10.1023/A:1018360026244

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摘要: Heterochromatic regions of chromosomes contain highly repetitive, tandemly arranged DNA sequences that undergo very rapid variation compared to unique are predominantly conserved. In this study the chromosomal basis speciation has been looked at in terms repeat sequences. We have hybridized twenty-one chromosome-specific human alphoid satellite probes metaphase spreads chimpanzee (Pan troglodytes), gorilla (Gorilla gorilla), and orangutan (Pongo pygmaeus) investigate evolutionary relationship heterochromatic among such hominoid species. The majority did not hybridize their corresponding equivalent chromosome but presented hybridization signals on non-corresponding chromosomes. Such observations suggest changes may occurred ancestral sequence, resulting divergence great ape

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