Gastrointestinal Disorders in Women

作者: Rita Gustafsson

DOI:

关键词:

摘要: Abstract: This doctoral thesis has sought to clarify the influence of gender in gastrointestinal (GI) disorders. Women with different hormone profiles were investigated, their colonic microbiota was characterized, and impact lifestyle risk factors for GI disease examined. In a pilot study, relation between vaginal rectal lactobacilli flora levels investigated 20 fertile postmenopausal women. No correlation found overall Lactobacillus species vagina rectum, no variations sex found. L. plantarum most often both women, crispatus more women than that We characterized mucosa-associated ascending colon two collagenous colitis. After cloning sequencing bacterial 16S rRNA genes, we composition similar healthy woman consists predominance Firmicutes Bacteroidetes. Interestingly, patients had high proportion potentially pathogenic Bacteroides clones related Clostridium clostridioforme. Gastroparesis esophageal dysmotility are common complications diabetes mellitus symptomatic asymptomatic patients. cross-sectional evaluated gastric motility, symptoms, secondary complications, plasma biomarkers consecutive mellitus. an unexpectedly prevalence dysmotility, which presented as strong association retinopathy. Furthermore, majority suffered from symptoms not associated objectively measured A total 131 female microscopic colitis (MC) examined regard smoking alcohol habits compared population-based controls. The main finding current – independently other increased developing persistent MC or concomitant irritable bowel syndrome (IBS)-like but development solely without IBS symptoms. Past transient MC. Taken together, some disorders obvious hormonal explanation could be found, although sensitive influences. is individuals, higher Bacteroides. Men have same amount when consecutively. Esophageal gastroparesis mellitus, it strongly Smoking important factor factors.

参考文章(294)
Ritva M. Koskela, Tuomo J. Karttunen, Seppo E. Niemelä, Juhani K. Lehtola, Jorma Ilonen, Riitta A. Karttunen, Human leucocyte antigen and TNFα polymorphism association in microscopic colitis European Journal of Gastroenterology & Hepatology. ,vol. 20, pp. 276- 282 ,(2008) , 10.1097/MEG.0B013E3282F2468D
MARY G. METCALF, R. A. DONALD, J. H. LIVESEY, Pituitary-ovarian function in normal women during the menopausal transition. Clinical Endocrinology. ,vol. 14, pp. 245- 255 ,(1981) , 10.1111/J.1365-2265.1981.TB00193.X
Martin Almquist, Anne-Greth Bondeson, Lennart Bondeson, Johan Malm, Jonas Manjer, Serum levels of vitamin D, PTH and calcium and breast cancer risk—a prospective nested case–control study International Journal of Cancer. ,vol. 127, pp. 2159- 2168 ,(2010) , 10.1002/IJC.25215
Hye–Kyung Jung, Rok Seon Choung, G. Richard Locke, Cathy D. Schleck, Alan R. Zinsmeister, Lawrence A. Szarka, Brian Mullan, Nicholas J. Talley, The incidence, prevalence and outcomes of patients with gastroparesis in Olmsted County, Minnesota from 1996 to 2006 Gastroenterology. ,vol. 136, pp. 1225- 1233 ,(2009) , 10.1053/J.GASTRO.2008.12.047
J. Hee, J. MacNaughton, M. Bangah, H.G. Burger, Perimenopausal patterns of gonadotrophins, immunoreactive inhibin, oestradiol and progesterone Maturitas. ,vol. 18, pp. 9- 20 ,(1993) , 10.1016/0378-5122(93)90026-E
Julia Borg, Olle Melander, Linda Johansson, Kerstin Uvnäs-Moberg, Jens F Rehfeld, Bodil Ohlsson, Gastroparesis is associated with oxytocin deficiency, oesophageal dysmotility with hyperCCKemia, and autonomic neuropathy with hypergastrinemia BMC Gastroenterology. ,vol. 9, pp. 17- 17 ,(2009) , 10.1186/1471-230X-9-17
R. Satokari, T. Grönroos, K. Laitinen, S. Salminen, E. Isolauri, Bifidobacterium and Lactobacillus DNA in the human placenta. Letters in Applied Microbiology. ,vol. 48, pp. 8- 12 ,(2009) , 10.1111/J.1472-765X.2008.02475.X
Jan L. Shifren, Isaac Schiff, The Aging Ovary Journal of Women's Health & Gender-Based Medicine. ,vol. 9, pp. 3- 7 ,(2000) , 10.1089/152460900318795
M. Zutshi, T. L. Hull, J. Bast, J. Hammel, Female Bowel Function: The Real Story Diseases of the Colon & Rectum. ,vol. 50, pp. 351- 358 ,(2007) , 10.1007/S10350-006-0758-0
Marcus J. Claesson, Douwe van Sinderen, Paul W. O'Toole, The genus Lactobacillus--a genomic basis for understanding its diversity. Fems Microbiology Letters. ,vol. 269, pp. 22- 28 ,(2007) , 10.1111/J.1574-6968.2006.00596.X