作者: Rita Gustafsson
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摘要: Abstract: This doctoral thesis has sought to clarify the influence of gender in gastrointestinal (GI) disorders. Women with different hormone profiles were investigated, their colonic microbiota was characterized, and impact lifestyle risk factors for GI disease examined. In a pilot study, relation between vaginal rectal lactobacilli flora levels investigated 20 fertile postmenopausal women. No correlation found overall Lactobacillus species vagina rectum, no variations sex found. L. plantarum most often both women, crispatus more women than that We characterized mucosa-associated ascending colon two collagenous colitis. After cloning sequencing bacterial 16S rRNA genes, we composition similar healthy woman consists predominance Firmicutes Bacteroidetes. Interestingly, patients had high proportion potentially pathogenic Bacteroides clones related Clostridium clostridioforme. Gastroparesis esophageal dysmotility are common complications diabetes mellitus symptomatic asymptomatic patients. cross-sectional evaluated gastric motility, symptoms, secondary complications, plasma biomarkers consecutive mellitus. an unexpectedly prevalence dysmotility, which presented as strong association retinopathy. Furthermore, majority suffered from symptoms not associated objectively measured A total 131 female microscopic colitis (MC) examined regard smoking alcohol habits compared population-based controls. The main finding current – independently other increased developing persistent MC or concomitant irritable bowel syndrome (IBS)-like but development solely without IBS symptoms. Past transient MC. Taken together, some disorders obvious hormonal explanation could be found, although sensitive influences. is individuals, higher Bacteroides. Men have same amount when consecutively. Esophageal gastroparesis mellitus, it strongly Smoking important factor factors.