Prognostic and diagnostic value of epithelial to mesenchymal transition markers in pulmonary neuroendocrine tumors
作者： Jose A Galván , Aurora Astudillo , Aitana Vallina , Guillermo Crespo , Maria Victoria Folgueras
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摘要: Background Pulmonary neuroendocrine tumors (Pulmonary NETs) include a wide spectrum of tumors, from the low-grade typical carcinoid (TC) and intermediate-grade atypical (AC), to high-grade large-cell carcinoma (LCNEC) small-cell (SCLC). Epithelial Mesenchymal Transition (EMT) is process initially recognised during several critical stages embryonic development, which has more recently been implicated in promoting invasion metastasis. The initial stage EMT begins with deregulation adhesion molecules, such as E-cadherin, due transcriptional repression carried out by factors Snail family members, Twist Foxc2.
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core.ac.uk 参考文章(43)
Alexander Gheldof, Geert Berx, Cadherins and epithelial-to-mesenchymal transition. Progress in Molecular Biology and Translational Science. ,vol. 116, pp. 317- 336 ,(2013) , 10.1016/B978-0-12-394311-8.00014-5
Satoshi Utsuki, Yuichi Sato, Hidehiro Oka, Benio Tsuchiya, Sachio Suzuki, Kiyotaka Fujii, Relationship between the expression of E-, N-cadherins and beta-catenin and tumor grade in astrocytomas. Journal of Neuro-oncology. ,vol. 57, pp. 187- 192 ,(2002) , 10.1023/A:1015720220602
Natasha Rekhtman, Neuroendocrine tumors of the lung: an update. Archives of Pathology & Laboratory Medicine. ,vol. 134, pp. 1628- 1638 ,(2010) , 10.1043/2009-0583-RAR.1
L. Vlahova, Y. Doerflinger, R. Houben, J.C. Becker, D. Schrama, C. Weiss, M. Goebeler, P. Helmbold, S. Goerdt, W.K. Peitsch, P‐cadherin expression in Merkel cell carcinomas is associated with prolonged recurrence‐free survival British Journal of Dermatology. ,vol. 166, pp. 1043- 1052 ,(2012) , 10.1111/J.1365-2133.2012.10853.X
Johan H van Es, Nick Barker, Hans Clevers, YOU WNT SOME, YOU LOSE SOME: ONCOGENES IN THE WNT SIGNALING PATHWAY Current Opinion in Genetics & Development. ,vol. 13, pp. 28- 33 ,(2003) , 10.1016/S0959-437X(02)00012-6
C. Salon, D. Moro, S. Lantuejoul, P.Y. Brichon, H. Drabkin, C. Brambilla, E. Brambilla, E-cadherin-β-catenin adhesion complex in neuroendocrine tumors of the lung: a suggested role upon local invasion and metastasis Human Pathology. ,vol. 35, pp. 1148- 1155 ,(2004) , 10.1016/J.HUMPATH.2004.04.015
Victor E. Gould, Jan Vincents Johannessen, Classification of Tumors Ultrastructural Pathology. ,vol. 1, ,(1980) , 10.3109/01913128009141431
Daniele Vergara, Benjamin Merlot, Jean-Philippe Lucot, Pierre Collinet, Denis Vinatier, Isabelle Fournier, Michel Salzet, Epithelial–mesenchymal transition in ovarian cancer Cancer Letters. ,vol. 291, pp. 59- 66 ,(2010) , 10.1016/J.CANLET.2009.09.017
M. ILYAS, I. P. M. TOMLINSON, THE INTERACTIONS OF APC, E‐CADHERIN AND β‐CATENIN IN TUMOUR DEVELOPMENT AND PROGRESSION The Journal of Pathology. ,vol. 182, pp. 128- 137 ,(1997) , 10.1002/(SICI)1096-9896(199706)182:2<128::AID-PATH839>3.0.CO;2-Q
Riitta Kaarteenaho, Elisa Lappi-Blanco, Siri Lehtonen, Epithelial N-cadherin and nuclear β-catenin are up-regulated during early development of human lung BMC Developmental Biology. ,vol. 10, pp. 113- 113 ,(2010) , 10.1186/1471-213X-10-113