Molecular nuclear imaging: the radiopharmaceuticals (review).

作者: Seyed K. Imam

DOI: 10.1089/CBR.2005.20.163

关键词:

摘要: Application of the nuclear approach for detection inherited diseases is an important goal medicine and will likely result in breakthrough, which will, hopefully, lead to improved diagnoses genetic defects objective evaluations efficacy therapeutic strategies. Although still largely research realm, molecular imaging process emerging as a vital component diagnosis disease monitoring therapy. The clinical has made major advancements direction targeted In past few years, exponential achievements have been accomplished development agents, described below.

参考文章(43)
David J. Yang, Seyfettin Ilgan, Tetsuya Higuchi, Fereshteh Zareneyrizi, Chang‐Sok Oh, Chun‐Wei Liu, E. Edmund Kim, Donald A. Podoloff, Noninvasive assessment of tumor hypoxia with 99mTc labeled metronidazole. Pharmaceutical Research. ,vol. 16, pp. 743- 750 ,(1999) , 10.1023/A:1018836911013
Eric O. Aboagye, Frank Brady, O. Clyde Hutchinson, Pat M. Price, Henryk Barthel, Sajinder K. Luthra, Marcel C. Cleij, Qimin He, David R. Collingridge, Safiye Osman, 3'-deoxy-3'-[18F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography. Cancer Research. ,vol. 63, pp. 3791- 3798 ,(2003)
Ronald G. Blasberg, Juri Gelovani (Tjuvajev), Molecular-genetic imaging: a nuclear medicine-based perspective. Molecular Imaging. ,vol. 1, pp. 280- 300 ,(2002) , 10.1162/153535002760235472
Renee M Moadel, Andrew V Nguyen, Elaine Y Lin, Ping Lu, Joseph Mani, M Donald Blaufox, Jeffrey W Pollard, Ekaterina Dadachova, Positron emission tomography agent 2-deoxy-2-[18F]fluoro-D-glucose has a therapeutic potential in breast cancer. Breast Cancer Research. ,vol. 5, pp. 1- 7 ,(2003) , 10.1186/BCR643
Mark Muzi, Peter Rabinowitz, Lanell M. Peterson, Jeffrey M. Pugsley, Rodney A. Schmidt, Hubert Vesselle, Douglas E. Wood, John Grierson, Eric Vallières, In Vivo Validation of 3′deoxy-3′-[18F]fluorothymidine ([18F]FLT) as a Proliferation Imaging Tracer in Humans: Correlation of [18F]FLT Uptake by Positron Emission Tomography with Ki-67 Immunohistochemistry and Flow Cytometry in Human Lung Tumors Clinical Cancer Research. ,vol. 8, pp. 3315- 3323 ,(2002)
V J Lowe, J W Fletcher, L Gobar, M Lawson, P Kirchner, P Valk, J Karis, K Hubner, D Delbeke, E V Heiberg, E F Patz, R E Coleman, Prospective investigation of positron emission tomography in lung nodules. Journal of Clinical Oncology. ,vol. 16, pp. 1075- 1084 ,(1998) , 10.1200/JCO.1998.16.3.1075
George H. Hinkle, John K. Burgers, Charles E. Neal, John H. Texter, Daniel Kahn, Richard D. Williams, Robert Maguire, Barbara Rogers, John O. Olsen, Robert A. Badalament, Multicenter radioimmunoscintigraphic evaluation of patients with prostate carcinoma using indium‐111 capromab pendetide Cancer. ,vol. 83, pp. 739- 747 ,(1998) , 10.1002/(SICI)1097-0142(19980815)83:4<739::AID-CNCR16>3.0.CO;2-T
F. G. Blankenberg, P. D. Katsikis, J. F. Tait, R. E. Davis, L. Naumovski, K. Ohtsuki, S. Kopiwoda, M. J. Abrams, M. Darkes, R. C. Robbins, H. T. Maecker, H. W. Strauss, In vivo detection and imaging of phosphatidylserine expression during programmed cell death Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 6349- 6354 ,(1998) , 10.1073/PNAS.95.11.6349
T. H. A. Arulampalam, S. K. Luthra, I. Taylor, D. L. Francis, D. Visvikis, P. J. Ell, C. Townsend, D. C. Costa, Potential impact of [18F]3'-deoxy-3'-fluorothymidine versus [18F]fluoro-2-deoxy-D-glucose in positron emission tomography for colorectal cancer European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 30, pp. 988- 994 ,(2003) , 10.1007/S00259-003-1187-0