Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles.

作者: Massimo Bonora , Mariusz R. Wieckowski , David A. Sinclair , Guido Kroemer , Paolo Pinton

DOI: 10.1038/S41569-018-0074-0

关键词:

摘要: … −/− myocardium to undergo regulated necrosis upon mitochondrial permeability transition (MPT) … regulated necrosis 64,71 (see below). Thus, sirtuins support cardiac fitness by affecting …

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