Mitotic Defects Lead to Neuronal Aneuploidy and Apoptosis in Frontotemporal Lobar Degeneration Caused by MAPT Mutations.
作者： Julbert Caneus , Antoneta Granic , Rosa Rademakers , Dennis W. Dickson , Christina M. Coughlan
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摘要: Our studies of MAPT mutations that cause frontotemporal lobar degeneration reveal a neurodegenerative pathway in which neurons and glia exhibit mitotic spindle abnormalities, chromosome mis-segrega...
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