Phytochemicals and Cancer – Possible Molecular Targets of Phytochemicals in Cancer Prevention and Therapy

Siti-Fauziah Hendrayani, Huda H. Al-Khalaf, Abdelilah Aboussekhra, Curcumin Triggers p16-Dependent Senescence in Active Breast Cancer-Associated Fibroblasts and Suppresses Their Paracrine Procarcinogenic Effects Neoplasia. ,vol. 15, pp. 631- 640 ,(2013) , 10.1593/NEO.13478

Danica L. Rowe, Tuba Ozbay, Ruth M. O'Regan, Rita Nahta, Modulation of the BRCA1 Protein and Induction of Apoptosis in Triple Negative Breast Cancer Cell Lines by the Polyphenolic Compound Curcumin Breast Cancer: Basic and Clinical Research. ,vol. 3, pp. 61- 75 ,(2009) , 10.4137/BCBCR.S3067

Mareike Ströfer, Wolfgang Jelkmann, Reinhard Depping, Curcumin decreases survival of Hep3B liver and MCF-7 breast cancer cells: the role of HIF. Strahlentherapie Und Onkologie. ,vol. 187, pp. 393- 400 ,(2011) , 10.1007/S00066-011-2248-0

Priya Ranjan Debata, Mario R. Castellanos, Jimmie E. Fata, Sarah Baggett, Sritha Rajupet, Anita Szerszen, Sultana Begum, Anita Mata, Vundavalli V. Murty, Lynne M. Opitz, Probal Banerjee, A novel curcumin-based vaginal cream Vacurin selectively eliminates apposed human cervical cancer cells. Gynecologic Oncology. ,vol. 129, pp. 145- 153 ,(2013) , 10.1016/J.YGYNO.2012.12.005

Chandan Rana, Vivek Vaish, Honit Piplani, Bimla Nehru, Sankar Nath Sanyal, None, Nuclear Factor-κB is expressed in early colon cancer and its down-regulation by Curcumin and Diclofenac is associated with the suppression of proliferation and the induction of apoptosis Biomedicine & Preventive Nutrition. ,vol. 2, pp. 228- 238 ,(2012) , 10.1016/J.BIONUT.2012.07.004

Anna Lewinska, Jagoda Adamczyk, Justyna Pajak, Sylwia Stoklosa, Barbara Kubis, Paulina Pastuszek, Ewa Slota, Maciej Wnuk, Curcumin-mediated decrease in the expression of nucleolar organizer regions in cervical cancer (HeLa) cells Mutation Research-genetic Toxicology and Environmental Mutagenesis. ,vol. 771, pp. 43- 52 ,(2014) , 10.1016/J.MRGENTOX.2014.07.001

Jenifer I. Fenton, Sarah J. McCaskey, Curcumin and docosahexaenoic acid block insulin-induced colon carcinoma cell proliferation Prostaglandins, Leukotrienes and Essential Fatty Acids. ,vol. 88, pp. 219- 226 ,(2013) , 10.1016/J.PLEFA.2012.11.010

Sojung Park, Dong Hyung Cho, Ladislav Andera, Nayoung Suh, Inki Kim, Curcumin enhances TRAIL-induced apoptosis of breast cancer cells by regulating apoptosis-related proteins. Molecular and Cellular Biochemistry. ,vol. 383, pp. 39- 48 ,(2013) , 10.1007/S11010-013-1752-1

Hao Liu, Bin-Hua Zhou, Xu Qiu, Hong-Sheng Wang, Fan Zhang, Rui Fang, Xian-Feng Wang, Shao-Hui Cai, Jun Du, Xian-Zhang Bu, T63, a new 4-arylidene curcumin analogue, induces cell cycle arrest and apoptosis through activation of the reactive oxygen species-FOXO3a pathway in lung cancer cells. Free Radical Biology and Medicine. ,vol. 53, pp. 2204- 2217 ,(2012) , 10.1016/J.FREERADBIOMED.2012.10.537

Ajaikumar B. Kunnumakkara, Preetha Anand, Bharat B. Aggarwal, Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins Cancer Letters. ,vol. 269, pp. 199- 225 ,(2008) , 10.1016/J.CANLET.2008.03.009