Cloning and Characterization of DNAs with Palindromic Sequences

摘要: A sentence contains an ordered set of letters that is interpreted by reading in one direction, but a palindromic such as “Madam I’m Adam” can be read either direction. Palindromic sentences are relatively rare because languages use large number and we normally write sense. The example given above, only three (apart from the central I) conveys limited amount information. By contrast, DNA composed four bases, does not always make sense (as defined encoded polypeptide) direction (though 3′ — 5′ on strand to give mRNA with polarity). palindrome respect double sequence two-fold rotational symmetry shown Figure 1. This has consequence polarity left right identical same left. Another way thinking about it two halves repeated inverted orientation each other. It repeat no unique separating sequences. Many short palindromes exist genomes best known recognition targets for type II restriction-modification systems widely used genetic engineering. Some imperfect other proteins transcriptional regulators or recombinases.