Rectal cancer and ulcerative colitis: does it change the therapeutic approach?

摘要: Objective  The aim of this study was to examine the incidence coexisting colorectal cancer in ulcerative colitis a population patients undergoing ileal pouch anal anastomosis. frequency rectal population, surgical intervention, general outcomes and recurrence are described. Methods  Data on 1850 restorative proctocolectomy from 1983 2001 were reviewed. Information gathered data department's pelvic database, as well pathology reports. Follow-up questionnaires routinely sent part database included analysis determine current functional status. Mean follow-up period 7.5 years after surgery. Results  Seventy had at time IPAA. 7 (10%) cancers incidental. Pre-operative duration disease 18.6 years. Twenty-six cancers. most common form anastomosis mucosectomy, especially pre-operatively known or low lying dysplasia. Preferred technique for mucosal (UC) high ligation mesenteric vessels with radical colectomy taped occlusion rectum irrigation stump Turnbull solution prior mucosectomy. Patients Stage 3 received postoperative chemotherapy. Post-operative radiation therapy not commonly recommended. Five 70 deceased metastatic colon cancer; 55 confirmed alive good excellent function range 1–17 years. Conclusion  Restorative is successful approach UC. When appropiate used cancer, along adjuvant chemotherapy when appropriate, prognosis very good.