Assessment of medication management capacity in a predominantly African American and Caribbean American sample of adults with intractable epilepsy.

摘要: Abstract Introduction Suboptimal or partial adherence to antiepileptic drugs (AEDs) is an avoidable cause of seizures and deleterious outcomes in epilepsy. As self-rated may be unreliable, suboptimal go undetected. This study assessed generalizability a performance-based measure medication management patients with intractable Materials methods Participants were 50 adults (age = 42 ± 14 years, 60% female, 82% Black, 20% Hispanic/Latino) ≥ 2 the preceding 6 months. Antiepileptic drug was electronically monitored for one month via Medication Event Monitoring Systems (MEMS) (1 = very poor 6 = excellent). The Management Ability Assessment (MMAA) administered at follow-up scored by raters blind results. Spearman correlations Poisson regressions their associations. Results On average, participants self-reported good-to-very good adherence. According MEMS, took AEDs as prescribed 73% time; most (58%) missed ≥ 3 doses. MMAA demonstrated strong internal consistency (Kuder-Richardson 20 = 0.81) associated MEMS: percentage days doses taken correctly (rs = 0.29, p = 0.04) frequency (rs = − 0.31, p = 0.03). not showed that self-ratings performance accounted unique variance AED Conclusions These findings provide evidence MMAA's criterion validity capacity manage AEDs. It prove useful cases where suspected but unreported patients. Its lack significant association consistent prior reports; however, future studies should replicate these larger samples.