Immunocontraception of captive exotic species. I. Przewalski's horses (Equus przewalskii) and banteng (Bos javanicus)
作者： Jay F. Kirkpatrick , Waltraut Zimmermann , Lydia Kolter , I. K. M. Liu , J. W. Turner
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摘要: A contraceptive vaccine made of porcine zonae pellucidae (PZP) was tested in three Przewalski's mares and five banteng cows. The antigen consisted the complete family glycoproteins zona pellucida, including sperm receptor ZP3. All were inoculated with 2 or 3 i.m. injections approximately 65 μg given over a 6 week period. Two other received inoculations only 35 on same schedule. cows pregnant at time inoculation. No new pregnancies, as result postinoculation breedings, occurred among either 36 months after for 24 inoculations. One pregnancy resulted two receiving antigen. Differences fertility between treated control preinoculation reproductive performance significant (P < 0.05). Urinary ovarian steroid metabolites behavioral observations indicated follicular development ovulations occurring during year following PZP immunization produced progressively elevated anti-PZP antibodies both species, which provided protection. appears to be an effective form contraception species. © 1995 Wiley-Liss, Inc.
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sci-hub.se 参考文章(26)
R.J. AITKEN, D.W. RICHARDSON, M. HULME, IMMUNOLOGICAL INTERFERENCE WITH THE PROPERTIES OF THE ZONA PELLUCIDA Immunological Aspects of Reproduction in Mammals. pp. 305- 325 ,(1984) , 10.1016/B978-0-408-10865-2.50022-0
J. F. Kirkpatrick, J. W. Turner, I. K. M. Liu, Remotely-delivered immunocontraception in feral horses. Wildlife Society Bulletin. ,vol. 18, pp. 326- 330 ,(1990)
J. F. Kirkpatrick, J. W. Turner, I. M. K. Liu, M. Bernoco, Antigen recognition in feral mares previously immunized with porcine zonae pellucidae. Journal of reproduction and fertility. ,vol. 44, pp. 321- 325 ,(1991)
M. Paterson, R.J. Aitken, Development of vaccines targeting the zona pellucida Current Opinion in Immunology. ,vol. 2, pp. 743- 747 ,(1990) , 10.1016/0952-7915(90)90043-G
S. L. Monfort, N. P. Arthur, D. E. Wildt, Monitoring ovarian function and pregnancy by evaluating excretion of urinary oestrogen conjugates in semi-free-ranging Przewalski's horses (Equus przewalskii). Reproduction. ,vol. 91, pp. 155- 164 ,(1991) , 10.1530/JRF.0.0910155
Bonnie S. Dunbar, Nate J. Wardrip, Jerry L. Hedrick, Isolation, physicochemical properties, and macromolecular composition of zona pellucida from porcine oocytes. Biochemistry. ,vol. 19, pp. 356- 365 ,(1980) , 10.1021/BI00543A017
R. B. L. Gwatkin, O. F. Andersen, D. T. Williams, Large scale isolation of bovine and pig zonae pellucidae: Chemical, immunological, and receptor properties Gamete Research. ,vol. 3, pp. 217- 231 ,(1980) , 10.1002/MRD.1120030304
Janine E. Voisin, Radslav G. Kinsky, Guy A. Voisin, Maternal alloimmune reactions towards the murine conceptus and graft-versus-host reaction (GVHR). II. Inhibition of priming by placental extracts. Journal of Reproductive Immunology. ,vol. 9, pp. 85- 94 ,(1986) , 10.1016/0165-0378(86)90002-1
P.F. Daels, D.C. Ammon, G.H. Stabenfeldt, I.K.M. Liu, J.P. Hughes, B.L. Lasley, URINARY AND PLASMA ESTROGEN CONJUGATES, ESTRADIOL AND ESTRONE CONCENTRATIONS IN NONPREGNANT AND EARLY PREGNANT MARES Theriogenology. ,vol. 35, pp. 1001- 1017 ,(1991) , 10.1016/0093-691X(91)90310-A
Akiko Hasegawa, Koji Koyama, Miyuki Inoue, Tadashi Takemura, Shinzo Isojima, Antifertility effect of active immunization with ZP4 glycoprotein family of porcine zona pellucida in hamsters Journal of Reproductive Immunology. ,vol. 22, pp. 197- 210 ,(1992) , 10.1016/0165-0378(92)90016-W