Cerebral Mechanisms and Neurogenic Hypertension in Man, with Special Reference to Baroreceptor Control

摘要: Publisher Summary This chapter presents a review of the literature concerning neurological disorders that may be associated with an increased blood pressure. Three types neurogenic hypertension are discussed. In each these types, particular structure medulla oblongata appears to affected. For Cushing response, stretch-sensitive area under floor fourth ventricle is essential. probably also sensitive reduction capillary flow. The original response only occurs when intracranial pressure reaches level arterial However, same can elicited by transaxial distortion lower brain stem, and threshold substantially lowered in cases space-occupying lesions, there gradient between supratentorial space posterior fossa due obstruction cerebral spinal fluid (CSF) flow across tentorial incisura. Experimental evidence has demonstrated loss baroreceptor control labile without change heart rate produced chronic experiments cat bilateral destruction nucleus tractus solitarii (NTS). Another type hypertension, tachycardia, described patients bulbar poliomyelitis. Neuropathological studies several authors lead conclusion cardio-vascular disturbances damage magnocellular medial part reticular formation.